HEMATOLOGY - MOLECULAR BIOLOGY

Thursday, 28/11/2024, 14:48 GMT+7

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Title

Hematological diseases

Hematologic disorders are a group of diseases that affect the blood and blood-forming organs such as the bone marrow. These disorders affect the number, size, and function of blood cells including red blood cells, white blood cells, and platelets.

Hematology test information

NGS technique

Bone marrow panel (AML, MDS, CML, MPN)
FLT3 ITD High-Low
CEBPA Bialen

RT-PCR, Sanger technique

PCR of 4 gene combinations in AML
PCR of 4 gene combinations in ALL
NPM1 gene mutation (exon 12)
CEBPA gene mutation

RQ-PCR technique

Quantification of minor BCR/ABL gene
TEL/AML1 gene quantification
E2A/PBX gene quantification
MLL/AF4 gene quantification
MLL/AF9 gene quantification
Quantification of MYH11/CBFB type A gene
Quantification of PML-RARA gene type BCR1, BCR2, BCR3
AML1-ETO gene quantification
Quantification of NPM1 type A gene
FLT3-ITD Gene Quantification (DNA Fragment)

FISH, Karyotyping

Fish t(12;21)(p13;q22)
Fish t(1;19)(q23;p13)
Fish t(9;22)(q34;q11)
FISH 11q23 rearrangement

Hematology test price list information

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DAI PHUOC GENERAL CLINIC

DEPARTMENT OF MOLECULAR BIOLOGY

LIST OF MOLECULAR BIOLOGY TESTS

HEMATOLOGY

I. Tests and techniques for performing NGS:

STT Test name Time of execution Sample Price

STT	Test name	Time of execution	Sample	Price
1	NGS myeloid panel (AML, MDS, CML, MPN)	4-5 weeks	Blood, marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	12.000.0000
2	FLT3 ITD High- Low	4-5 weeks	Blood, marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	3.600.000
3	CEBPA Bialen	4-5 weeks	Blood, marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	6.500.000

NGS myeloid panel (AML, MDS, CML, MPN)

4-5 weeks

Blood, marrow

EDTA anticoagulant

2 ml x 1 tube

Room temperature

Sent within 4 hours

12.000.0000

FLT3 ITD High- Low

4-5 weeks

Blood, marrow

EDTA anticoagulant

2 ml x 1 tube

Room temperature

Sent within 4 hours

3.600.000

CEBPA Bialen

4-5 weeks

Blood, marrow

EDTA anticoagulant

2 ml x 1 tube

Room temperature

Sent within 4 hours

6.500.000

II. Sanger tests and techniques:

STT	Test name	Time of execution	Sample	Price
2	MPL gene mutation	10 days	Blood, marrow EDTA anticoagulant 2 ml x 1 tube Room temperature	1.500.000
3	CALR gene mutation	10 days	Blood EDTA anticoagulant 2 ml x 1 tube Room temperature	1.500.000
4	JAK2 exon 12 gene mutation	10 days	Blood EDTA anticoagulant 2 ml x 1 tube Room temperature	1.500.000
5	TPMT gene mutation (Thiopurine-responsive)	10 days	Blood EDTA anticoagulant 2 ml x 1 tube Room temperature	2.500.000
6	NUDT15 gene mutation (exons 1 and 3) (Thiopurine-responsive)	10 days	Blood EDTA anticoagulant 2 ml x 1 tube Room temperature	2.500.000
7	FLT3 gene mutation (exons 14, 15, 20) (AML)	10 days	Blood, marrow EDTA anticoagulant 2 ml x 2 tubes Room temperature Sent within 4 hours	3.000.000
8	NPM1 gene mutation (exon 12) (AML)	10 days	Blood, marrow EDTA anticoagulant 2 ml x 2 tubes Room temperature Sent within 4 hours	2.000.000
9	CEBPA gene mutation (AML)	10 days	Blood, marrow EDTA anticoagulant 2 ml x 2 tubes Room temperature Sent within 4 hours	2.000.000
10	P53 Gene Mutation (Cancer)	10 days	Blood EDTA anticoagulant 2 ml x 1 tube Room temperature	4.000.000
11	IGHV gene mutation	10 days	Blood EDTA anticoagulant 2 ml x 1 tube Room temperature	2.500.000

IV. FISH tests and techniques:

STT	Test name	Time of execution	Sample	Price
1	FISH t(12;21)(p13;q22)	10 days	Blood, marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
2	FISH t(1;19)(q23;p13)	10 days	Blood, marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
3	FISH t(9;22)(q34;q11) NST Philadelphia	10 days	Blood, marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
4	FISH 11q23 rearrangement	10 days	Blood, marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
5	FISH t(15;17)(q24;q21)	10 days	Blood, marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
6	FISH t(8;21)(q21.3;q22)	10 days	Blood, marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
7	FISH inv(16)(p13q22)/t(16;16)(p13;q22)	10 days	Blood, marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
8	FISH 5q31	10 days	Blood, marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
9	FISH 7q31	10 days	Blood, marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
10	FISH: ATM Deletion	10 days	Blood, marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
11	FISH: 1p32/1q21	10 days	Blood, marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000

12	FISH: NST 17p13	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
13	FISH: NST 13q14-34	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
14	FISH: t(4;14)(p16;q32)	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
15	FISH: t(6;14)(p21;q32)	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
16	FISH: t(11;14)(q13;q32)	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
17	FISH: t(14;16)(q32;q23)	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
18	FISH: t(14;20)(q32;q11)	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
19	FISH: 6 probes in multiple myeloma	10 days	Marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	7.500.000
20	FISH: 7 probes in multiple myeloma	10 days	Marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	9.000.000
21	FISH: 8 probes in multiple myeloma	10 days	Marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	10.500.000
22	FISH: PDGFRB (HES)	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
23	FISH: FGFR1 (HES)	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000

24	FISH: JAK2 (HES)	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
25	FISH: CRLF2 (HES)	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
26	FISH: ABL2 (HES)	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
27	FISH: EPOR	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000
28	Other FISH probes (blood, bone marrow)	10 days	Blood , marrow HEPARIN antifreeze 2 ml x 1 tube Room temperature	1.500.000

VI. Tests and techniques for performing RT-PCR, RQ-PCR, ddPCR, ASO-PCR:

STT	Test name	Time of execution	Sample	Price
1	JAK2 V617F gene mutation (ddPCR)	15 days	Blood EDTA anticoagulant 2 ml x 1 tube Room temperature	1.250.000
2	BCR/ABL gene identification ( CML, ALL) (RT-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	1.000.000
3	BCR/ABL gene quantification ( RQ-PCR )	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	2.400.000
4	Quantification of minor BCR/ABL gene ( RQ-PCR )	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	2.000.000
5	PML/RARA gene identification ( RT-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	1.000.000
6	Quantitative BCR1 - type PML-RARA (RQ-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	2.000.000
7	Quantitative BCR2 - type PML-RARA (RQ-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	2.000.000
8	Quantitative BCR3 -type PML-RARA (RQ-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	2.000.000
9	AML1/ETO gene identification ( RT-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature sent in 4 hours	1.000.000
10	AML1/ETO gene quantification (R Q -PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature sent in 4 hours	2.000.000
11	Identification of CBFB/MYH11 gene (RT-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	1.000.000
12	Quantification of CBFB/MYH11 type A gene (R Q -PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	2.000.000
13	MLL/AF9 gene identification ( RT-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	1.000.000
14	4 gene clusters in AML (RT-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	2.500.000
15	4 gene clusters in ALL (RT-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	2.500.000
16	PCR to determine TEL/AML1 gene (RT-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	1.000.000
17	TEL/AML1 gene quantification (R Q -PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	2.000.000
18	PCR to determine E2A/PBX1 gene (RT-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	1.000.000
19	E2A/ PBX1 gene quantification (R Q -PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	2.000.000
20	PCR to determine MLL/AF4 gene (RT-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	1.000.000
21	MLL/AF4 gene quantification (R Q -PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	2.000.000
22	MLL/AF9 gene quantification (R Q -PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	2.000.000
23	Quantification of NPM1 type A gene (R Q -PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	2.000.000
24	Quantification of FLT3-ITD gene ( R Q -PCR DNA Fragment )	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	3.600.000
25	TEL/PDGFRB (HES) gene identification ( RT-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	1.000.000
26	X FIP1L1/PDGFRA (HES) gene identification (RT-PCR)	10 days	Blood , marrow EDTA anticoagulant 2 ml x 1 tube Room temperature Sent within 4 hours	1.000.000

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